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Table 4 MDDR-HOM activity classes used in the virtual screening experiments.

From: Evaluation of a Bayesian inference network for ligand-based virtual screening

Activity class Active molecules Pairwise similarity
Muscarinic (M1) agonists 848 0.206 0.098
NMDA receptor antagonists 1311 0.199 0.090
Nitric oxide synthase inhibitors 377 0.189 0.086
Dopamine beta-hydroxylase inhibitors 95 0.229 0.076
Aldose reductase inhibitors 882 0.232 0.096
Reverse transcriptase inhibitors 519 0.218 0.095
Aromatase inhibitors 513 0.229 0.117
Cyclooxygenase inhibitors 636 0.220 0.107
Phospholipase A2 inhibitors 704 0.224 0.111
Lipoxygenase inhibitors 2555 0.224 0.110
  1. Details as for Table 3.