From: Evaluation of a Bayesian inference network for ligand-based virtual screening
Activity class | Active molecules | Pairwise similarity | |
---|---|---|---|
Renin inhibitors | 474 | 0.592 | 0.109 |
Protein kinase C inhibitors | 142 | 0.565 | 0.277 |
Matrix metalloprotease inhibitors | 694 | 0.444 | 0.148 |
Angiotensin II AT1 antagonists | 724 | 0.443 | 0.131 |
HIV protease inhibitors | 1128 | 0.442 | 0.146 |
Substance P antagonists | 558 | 0.427 | 0.127 |
Thrombin inhibitors | 421 | 0.418 | 0.144 |
5HT1A antagonists | 592 | 0.399 | 0.134 |
Factor Xa inhibitors | 842 | 0.394 | 0.124 |
5HT3 antagonists | 220 | 0.377 | 0.175 |
Acetylcholine esterase inhibitors | 503 | 0.373 | 0.155 |
D2 antagonists | 910 | 0.367 | 0.116 |
Phosphodiesterase inhibitors | 596 | 0.359 | 0.136 |
Cyclooxygenase inhibitors | 965 | 0.324 | 0.139 |