Linkage Reaction | Fragment(s) |
---|---|
Amide bond formation or Urea formation | 2, 6, 8, 12 (from primary amine) or 16 (from secondary amine), 28 (only if aniline) |
Sulfonamide formation | 6, 12 (from primary amine) or 16 (from secondary amine) |
Ester formation | 2, 6, 8, 10 |
Reductive amination | 4 (the CH2 group from the aldehyde carbon), 12 (from primary amine) or 16 (from secondary amine) |