FCFP_6 Tanimoto similarity between the toxic compounds from NCGC and the Scripps compounds. In the Scripps data set, toxic compounds are red, non-toxic compounds, blue. In the histogram on the left the Scripps IC50 set was used as reference, on the right the Scripps percent inhibition set. For each compound from NCGC the highest similarity was retained with the Scripps compounds from each category. A similar distribution was obtained with the BCI fingerprints (not shown).