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Table 1 Average enrichment factors obtained in a retrospective virtual screen of the DUD-E database (no pooling)

From: USRCAT: real-time ultrafast shape recognition with pharmacophoric constraints

Method Enrichment Factors
1.0% 0.5% 0.25%
USR 5.00 6.71 8.84
ElectroShape 8.40 11.27 14.48
USRCAT 8.62 11.99 15.64
Circular FP 32.14 42.54 49.72
Path FP 24.50 35.14 44.27
Tree FP 19.28 28.98 38.59
MACCS166 20.90 28.85 36.60