TY - JOUR AU - Paul, S. M. AU - Mytelka, D. S. AU - Dunwiddie, C. T. AU - Persinger, C. C. AU - Munos, B. H. AU - Lindborg, S. R. AU - Schacht, A. L. PY - 2010 DA - 2010// TI - How to improve R&D productivity: the pharmaceutical Industry’s grand challenge JO - Nature Rev Drug Discov VL - 9 ID - Paul2010 ER - TY - JOUR AU - Pammolli, F. AU - Magazzini, L. AU - Riccaboni, M. PY - 2011 DA - 2011// TI - The productivity crisis in pharmaceutical R&D JO - Nature VL - 10 ID - Pammolli2011 ER - TY - BOOK AU - Pyzdek, T. PY - 2003 DA - 2003// TI - In The Six sigma handbook: The complete guide for greenbelts, blackbelts, and managers of All levels, 2nd revised edition PB - McGraw-Hill CY - New York ID - Pyzdek2003 ER - TY - JOUR AU - Johnstone, C. AU - Pairaudeau, G. AU - Pettersson, J. A. PY - 2011 DA - 2011// TI - Creativity, innovation and lean sigma: a controversial combination? JO - Drug Discov Today VL - 16 UR - https://doi.org/10.1016/j.drudis.2010.11.005 DO - 10.1016/j.drudis.2010.11.005 ID - Johnstone2011 ER - TY - JOUR AU - Chow, S. C. AU - Chang, M. PY - 2008 DA - 2008// TI - Adaptive Design Methods in Clinical Trials - A Review JO - Orphanet J Rare Dis VL - 3 UR - https://doi.org/10.1186/1750-1172-3-11 DO - 10.1186/1750-1172-3-11 ID - Chow2008 ER - TY - JOUR AU - Orloff, J. AU - Douglas, F. AU - Pinheiro, J. AU - Levinson, S. AU - Michael, B. M. AU - Chaturvedi, P. AU - Ette, E. AU - Gallo, P. AU - Hirsch, G. AU - Mehta, C. AU - Patel, N. AU - Sabir, S. AU - Springs, S. AU - Stanski, D. AU - Evers, M. R. AU - Fleming, E. AU - Singh, N. AU - Tramontin, T. AU - Golub, H. PY - 2009 DA - 2009// TI - The future of drug development: advancing clinical trial design JO - Nat Rev Drug Discov VL - 8 ID - Orloff2009 ER - TY - BOOK AU - Chang, M. PY - 2011 DA - 2011// TI - Monte Carlo simulation for the pharmaceutical industry PB - CRC Press CY - Boca Raton ID - Chang2011 ER - TY - JOUR AU - Jones, B. PY - 2009 DA - 2009// TI - The burden of knowledge and the ‘death of the renaissance Man’: is innovation getting harder? JO - Rev Econ Stat VL - 76 UR - https://doi.org/10.1111/j.1467-937X.2008.00531.x DO - 10.1111/j.1467-937X.2008.00531.x ID - Jones2009 ER - TY - JOUR AU - Nonaka, I. PY - 1991 DA - 1991// JO - The Knowledge-Creating Company. Harvard Bus Rev VL - 69 ID - Nonaka1991 ER - TY - JOUR AU - Nonaka, I. PY - 1994 DA - 1994// TI - A dynamic theory of organizational knowledge creation JO - Organ Sci VL - 5 UR - https://doi.org/10.1287/orsc.5.1.14 DO - 10.1287/orsc.5.1.14 ID - Nonaka1994 ER - TY - JOUR AU - Libby, R. AU - Blashfield, R. K. PY - 1978 DA - 1978// TI - Performance of a composite as a function of the number of judges JO - Organ Behav Hum Perform VL - 21 UR - https://doi.org/10.1016/0030-5073(78)90044-2 DO - 10.1016/0030-5073(78)90044-2 ID - Libby1978 ER - TY - JOUR AU - Hill, G. W. PY - 1982 DA - 1982// TI - Group versus individual performance: Are N+1 heads better than One? JO - Psychol Bull VL - 91 UR - https://doi.org/10.1037/0033-2909.91.3.517 DO - 10.1037/0033-2909.91.3.517 ID - Hill1982 ER - TY - JOUR AU - Garnier, J. P. PY - 2008 DA - 2008// TI - Rebuilding the R & D engine in Big pharma JO - Harvard Bus Rev VL - 86 ID - Garnier2008 ER - TY - JOUR AU - Lamm, H. AU - Trommsdorff, G. PY - 1973 DA - 1973// TI - Group versus individual performance on tasks requiring ideational proficiency (brainstorming): a review JO - Eur J Soc Psychol VL - 3 UR - https://doi.org/10.1002/ejsp.2420030402 DO - 10.1002/ejsp.2420030402 ID - Lamm1973 ER - TY - JOUR AU - Mullen, B. AU - Johnson, C. AU - Salas, E. PY - 1991 DA - 1991// TI - Productivity loss in brainstorming groups: a meta-analytic integration JO - Basic Appl Soc Psych VL - 12 UR - https://doi.org/10.1207/s15324834basp1201_1 DO - 10.1207/s15324834basp1201_1 ID - Mullen1991 ER - TY - JOUR AU - Berg, S. PY - 1993 DA - 1993// TI - Condorcet's Jury theorem JO - Dependence Among Jurers. Soc Choice Welf VL - 10 ID - Berg1993 ER - TY - JOUR AU - Berg, S. PY - 1993 DA - 1993// TI - Condorcet's Jury theorem revisited JO - Eur J Polit Econ VL - 9 UR - https://doi.org/10.1016/0176-2680(93)90010-R DO - 10.1016/0176-2680(93)90010-R ID - Berg1993 ER - TY - JOUR AU - Berend, D. AU - Parous, J. PY - 1998 DA - 1998// TI - When is Condorcet's jury theorem valid? JO - Soc Choice Welf VL - 15 UR - https://doi.org/10.1007/s003550050118 DO - 10.1007/s003550050118 ID - Berend1998 ER - TY - JOUR AU - Genest, C. AU - Zidek, V. PY - 1986 DA - 1986// TI - Combining probability distributions: a critique and an annotated bibliography JO - Stat Sci VL - 1 UR - https://doi.org/10.1214/ss/1177013825 DO - 10.1214/ss/1177013825 ID - Genest1986 ER - TY - JOUR AU - Adler, F. P. PY - 1960 DA - 1960// TI - Relationships between organization size and efficiency JO - Manage Sci VL - 7 UR - https://doi.org/10.1287/mnsc.7.1.80 DO - 10.1287/mnsc.7.1.80 ID - Adler1960 ER - TY - JOUR AU - Van de Ven, A. H. AU - Delbecq, A. L. PY - 1971 DA - 1971// TI - Nominal versus interacting group processes for committee decision making JO - Acad Manage J VL - 14 UR - https://doi.org/10.2307/255307 DO - 10.2307/255307 ID - Van de Ven1971 ER - TY - JOUR AU - Grofman, B. AU - Feld, S. L. PY - 1984 DA - 1984// TI - Group size and the performance of a composite group majority: statistical truths and empirical results JO - Organ Behav Hum Perform VL - 33 UR - https://doi.org/10.1016/0030-5073(84)90028-X DO - 10.1016/0030-5073(84)90028-X ID - Grofman1984 ER - TY - JOUR AU - Woolley, A. W. AU - Chabris, C. F. AU - Pentland, A. AU - Hashmi, N. AU - Malone, T. W. PY - 2010 DA - 2010// TI - Evidence for a collective intelligence factor in the performance of human groups JO - Science VL - 330 UR - https://doi.org/10.1126/science.1193147 DO - 10.1126/science.1193147 ID - Woolley2010 ER - TY - BOOK AU - Rogers, E. M. PY - 2003 DA - 2003// TI - Diffusion of innovations PB - Simon and Schuster CY - New York ID - Rogers2003 ER - TY - JOUR AU - Cuatrecasas, P. PY - 2006 DA - 2006// TI - Drug discovery in jeopardy JO - J Clin Invest VL - 116 UR - https://doi.org/10.1172/JCI29999 DO - 10.1172/JCI29999 ID - Cuatrecasas2006 ER - TY - STD TI - OriginPro, version 8.6. 2012, Northampton, MA: Origin Lab Corporation ID - ref26 ER - TY - JOUR AU - Little, J. D. C. PY - 1961 DA - 1961// TI - A proof of the queuing formula: L=λW JO - Oper Res VL - 9 UR - https://doi.org/10.1287/opre.9.3.383 DO - 10.1287/opre.9.3.383 ID - Little1961 ER - TY - JOUR AU - Beckon, W. N. AU - Parkins, C. AU - Maximovich, A. AU - Beckon, A. V. PY - 2008 DA - 2008// TI - A general approach to modeling biphasic relationships JO - Environ Sci Technol VL - 42 UR - https://doi.org/10.1021/es071148m DO - 10.1021/es071148m ID - Beckon2008 ER -