TB Mobile: a mobile app for anti-tuberculosis molecules with known targets

Table 1 Molecules active against Mtb evaluated in TB Mobile app

Name	Notes from literature	TB Mobile results most similar	Reference
L2-04	Proposed target is Alr	SahH (D-cycloserine ranked 12^th)	[45]
L2-05	Proposed target is Alr	SahH	[45]
L2-06	Proposed target is Alr	SahH	[45]
L2-10	Proposed target is Alr	DapA	[45]
L2-12	Proposed target is Alr	SahH	[45]
L2-13	Proposed target is Alr	ThiL	[45]
NC00094221	Proposed target is DfrA	EmbA, EmbB, EmbC (Isoniazid ranked 25^th (DfrA))	[46]
DNB1	DprE1/ DprE2	InhA	[49]
Mirandamycin	Proposed-quinol oxidase	FolP1, FolP2	[50]
cpd 3	Glyoxylase (rv0577)	FtsZ	[51]
377790	DprE1	ThiL	[9]
Pyridomycin	InhA	Def (InhA ranked 2^nd)	[43]
Gliotoxin	Not described	Mca (Molecule in database)	[9]
A039	Glycerol dependent	InhA	[9]
C215	MmpL3	Cyp51, Cyp121,Cyp130	[9]
Oxyphenbutazone	none	InhA	[48]
7759844	Mt-Guab2	InhA	[52]
GNF-NITD 46	Inhibit ATP homeostasis	Dxs1	[8]
GNF-NITD 82	Inhibit ATP homeostasis	CysH	[8]
GNF-NITD101	Inhibit ATP homeostasis	SahH	[8]

ISSN: 1758-2946