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Table 2 First line drugs active against Mtb evaluated in TB Mobile app and the top 3 molecules

From: TB Mobile: a mobile app for anti-tuberculosis molecules with known targets

Molecule Name 1st 2nd 3rd
Amikacin Amikacin (FusA1, FusA2, Tuf, EngA, Era) Kanamycin (FusA1, FusA2, Tuf, RplC, InfB) Streptomycin (FusA1, FusA2, Tuf, RplC)
Aminosalicylic acid Aminosalicylic acid (FolP1, FolP2) (Rv1885c) Nicotinamide (SahH)
Capreomycin 1A Capreomycin 1A (TlyA) Capreomycin 1B (RplJ, TlyA) Capreomycin (RplJ)
Capreomycin 1B Capreomycin 1B (RplJ, TlyA) Capreomycin (TlyA) Capreomycin (RplJ)
D-Cycloserine D-cycloserine (Alr) Ethambutol (EmbA, EmbB, EmbC) (DapA)
Ethambutol Ethambutol (EmbA, EmbB, EmbC) (DapA) D-cycloserine (Alr)
Ethionamide Ethionamide (InhA) Prothionamide (SahH) Nicotinamide (SahH)
Gatifloxacin Gatifloxacin (GyrA) Moxifloxacin (Murd, PurU) Ciprofloxacin (GyrA)
Isoniazid Isoniazid (InhA, KasA, DfrA) Nicotinamide (SahH) Ethionamide (InhA)
Kanamycin Kanamycin (FusA1, FusA2, Tuf, RplC, InfB) Amikacin (FusA1, FusA2, Tuf, EngA, Era) Streptomycin (FusA1, FusA2, Tuf, RplC)
Moxifloxacin Moxifloxacin (Murd, PurU) (GyrA) Gatifloxacin (GyrA)
Pyrazinamide Pyrazinamide (NedR) Pyrazinoic acid (deaD, Mfd, RecG, DinG, NedR) Nicotinamide (SahH)
Rifampin Rifampin (RpoB) Rifapentine (RpoB) Rifabutin (RpoB)
Streptomycin Streptomycin (FusA1, FusA2, Tuf, RplC) Amikacin (FusA1, FusA2, Tuf, EngA, Era) Kanamycin (FusA1, FusA2, Tuf, RplC, InfB)
  1. This illustrates they are in the app and that similar molecules with their targets are retrieved.