Figure 1

Molecular structures of: (a) Rosiglitzaone with tyrosine moiety (ssO), (b) Rosiglitzaone with tertiary alkylamine moiety (sssN), (c) AD-7075 and BRL48482 with oxazole moiety (aaO), and (d) Two carboxylic acid agonists with Fmoc-like moiety (aaaC). All moiety structures are colored in blue and the atom of the ES symbol is colored in red.