Skip to main content

Table 1 Kinase subsets

From: Inferring multi-target QSAR models with taxonomy-based multi-task learning

Identifier

Members

Size

Cluster sizes

TK/PI3

HCK, PIK3CA, SRC, ABL1

123

18, 20, 39, 22, 19, 5

MAPK

MAPK8, MAPK9, MAPK10

142

32, 24, 15, 28, 21, 22

PIM

PIM1, PIM2, PIM3,

   91

14, 10, 16, 17, 11, 23

PRKC

PRKCD, PRKCE, PRKCH

   99

12, 10, 7, 18, 35, 16

  1. Every compound of a subset has a pIC50 value for each kinase of the subset. The chemotype clusters were calculated with a 6-median clustering on the Tanimoto distance matrix.
Back to article page

Journal of Cheminformatics

ISSN: 1758-2946

Contact us