Figure 2

Distribution of the number of kinases as a function of compounds inhibiting the respective number of kinases. Compounds that lowered bioactivity of the kinase in question by 50% or more were considered active. Overall, kinases in the dataset were inhibited by 1 to 70 compounds in most cases. This indicates that our kinome dataset contains a wide range of kinases, including those that are promiscuous to multiple compounds as well as selective kinases.