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Table 1 The number of the scaffolds at the different levels of the Scaffold Tree for MDDR, ACD and TCMCD

From: Drug-likeness analysis of traditional Chinese medicines: 2. Characterization of scaffold architectures for drug-like compounds, non-drug-like compounds, and natural compounds from traditional Chinese medicines

Level No. of Scaffolds No. of non-duplicated Scaffolds
MDDR ACD TCMCD MDDR ACD TCMCD
Level 0 33558 33336 32893 1232 673 1047
Level 1 31780 29902 30722 6386 4588 4053
Level 2 26358 20483 25149 13840 7334 6351
Level 3 15749 11928 16848 11117 5641 5810
Level 4 5848 4544 8521 4686 2778 3866
Level 5 1250 1134 2753 1046 752 1563
Level 6 212 171 665 170 131 426
Level 7 53 39 165 26 37 114
Level 8 12 16 20 12 16 18
Level 9 0 5 13 0 5 11
Level 10 0 2 7 0 2 5
Level 11 0 0 3 0 0 3
Level 12 0 0 3 0 0 3
Level 13 0 0 1 0 0 1