From: Improving structural similarity based virtual screening using background knowledge
ECFP ext | MCS ext | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
1% | 5% | 10% | 1% | 5% | 10% | |||||||
Win | Loss | Win | Loss | Win | Loss | Win | Loss | Win | Loss | Win | Loss | |
HMGR | 10 | 0 | 10 | 0 | 10 | 0 | 5 | 0 | 5 | 0 | 5 | 0 |
ER | 8 | 2 | 10 | 0 | 9 | 1 | 10 | 0 | 10 | 0 | 10 | 0 |
PPAR γ | 9 | 1 | 9 | 1 | 9 | 1 | 9 | 1 | 10 | 0 | 9 | 1 |
P38 MAP | 9 | 1 | 10 | 0 | 10 | 0 | 10 | 0 | 10 | 0 | 9 | 1 |
TK | 10 | 0 | 9 | 1 | 8 | 2 | 9 | 1 | 9 | 1 | 9 | 1 |
FXa | 10 | 0 | 9 | 1 | 9 | 1 | 10 | 0 | 9 | 1 | 9 | 1 |
ADA | 10 | 0 | 6 | 4 | 10 | 0 | 8 | 1 | 8 | 1 | 8 | 1 |
DHFR | 8 | 2 | 10 | 0 | 10 | 0 | 10 | 0 | 10 | 0 | 10 | 0 |
ACHE | 9 | 1 | 9 | 1 | 9 | 1 | 10 | 0 | 10 | 0 | 9 | 1 |
COX-2 | 6 | 4 | 7 | 3 | 8 | 2 | 7 | 3 | 9 | 1 | 9 | 1 |
Sum | 89 | 11 | 89 | 11 | 92 | 8 | 88 | 6 | 90 | 4 | 87 | 7 |