Table 1 Top potential compounds for inhibition of platelet aggregation according to degree centrality of drug-target network
From: CVDHD: a cardiovascular disease herbal database for drug discovery and network pharmacology
| Rank | Compound | Degree | CAS NO. | Chemical name |
|---|---|---|---|---|
| 1 | CVDHD016293 | 6 | 62218-13-7 | (+)-α-viniferin |
| 2 | CVDHD027110 | 6 | N/A | hypericinate |
| 3 | CVDHD007020 | 6 | 54352-30-6 | tricrotonyltetramine |
| 4 | CVDHD012997 | 6 | N/A | blumeanine |
| 5 | CVDHD001236 | 5 | N/A | kadlongilactone B |
| 6 | CVDHD012285 | 5 | 225662-66-8 | hypericin radical cation |
| 7 | CVDHD002703 | 5 | 50838-55-6 | trisjuglone |
| 8 | CVDHD032784 | 5 | 55954-61-5 | pseudohypericine |
| 9 | CVDHD029497 | 5 | 7034-04-0 | tricrotonyltetramin |
| 10 | CVDHD002390 | 4 | N/A | 20(R)-21,24-Cyclo-3beta,25-dihydroxyldammar-23(24)-en-21-one |
| 11 | CVDHD014854 | 4 | N/A | longipedlactone F |
| 12 | CVDHD034764 | 4 | N/A | celastroline B alpha |
| 13 | CVDHD010515 | 4 | 123522-98-5 | isowithametelin |
| 14 | CVDHD014739 | 4 | N/A | eremodimer B |
| 15 | CVDHD025068 | 4 | N/A | bismorphine B |
| 16 | CVDHD017384 | 4 | 1253379-22-4 | dievodiamine |
| 17 | CVDHD021374 | 4 | N/A | lycochinine B |
| 18 | CVDHD025464 | 4 | 511-98-8 | solasodanol |
| 19 | CVDHD019403 | 4 | 129748-10-3 | incarvillateine |
| 20 | CVDHD019431 | 4 | 548-04-9 | hypericin |
| 21 | CVDHD029988 | 4 | 129225-31-6 | aminopropylcanavalmine |
| 22 | CVDHD009071 | 4 | 77646-14-1 | 3β,17α-Cinchophylline |
| 23 | CVDHD015834 | 4 | N/A | bismorphine A |
| 24 | CVDHD011497 | 4 | N/A | dihydro-18,19 3β,17β cinchophylline |