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Table 5 Performance of FINDSITE methods for 3,576 drug targets

From: Experimental validation of FINDSITEcomb virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders

Method (binding database)

Average EF0.01

# (%) of targets having EF0.01 > 1

FINDSITE (PDB)

31.7

1526 (43%)

FINDSITEX (DrugBank)

36.6

1714 (48%)

FINDSITEX (ChEMBL)

9.5

566 (16%)

FINDSITEfilt (PDB)

46.0

2080 (58%)

FINDSITEcomb

52.1

2333 (65%)

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