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Table 4 Retrieval of 11 targets of 4OH-Tamoxifen by i Drug

From: iDrug: a web-accessible and interactive drug discovery and design platform

Target name Reference Score PDB ID Rank(%)
Estrogen receptor-γ [52] 5.736 1VJB 0.01
Estradiol 17β-hydroxysteroid dehydrogenase 1 [53] 4.111 1I5R 0.26
Dihydrofolate reductase [54] 3.777 1DG7 0.45
Glutathione S-transferase A1 [55] 3.655 1GSF 0.73
Prostaglandin G/H synthase 2 [56] 3.411 1PXX 1.36
Liver carboxylesterase 1 [57] 3.344 1YA4 1.59
Protein kinase C theta type [58] 3.171 1XJD 2.18
Calmodulin [59] 2.974 1XA5 3.63
Collagenase 3 [60] 2.945 3I7I 4.57
Alcohol dehydrogenase E chain [60] 2.881 1MGO 7.37
3-alpha-(or20-beta)-hydroxysteroid dehydrogenase [61] 2.835 1HDC 9.87