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Table 1 Composition of the COX dataset

From: Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling

UniProt ID

Type

Organism

Number of bioactivities

% Compounds annotated

P23219

1

Homo sapiens

1,346

41.7

O62664

1

Box taurus

48

1.5

P22437

1

Mus musculus

50

1.5

O97554

1

Oryctolagus cuniculus

11

0.3

P05979

1

Ovis aries

442

13.7

Q63921

1

Rattus Norvegicus

23

0.7

P35354

2

Homo sapiens

2,311

71.6

O62698

2

Bos taurus

21

0.7

Q05769

2

Mus musculus

305

9.4

P79208

2

Ovis aries

341

10.6

P35355

2

Rattus Norvegicus

39

1.2

  1. The total number of bioactivities, after duplicate removal and selected from ChEMBL as described in Materials and methods, and of distinct compounds are 4,937 and 3,228 respectively. The last column indicates the percentage of the total number of distinct compounds (3,228) annotated on each target.