Table 2 Names and hepatotoxicity classes a of the drugs that matched the structural alerts defined in Table 1
Drug name | Class | Drug name | Class | Drug name | Class | Drug name | Class |
|---|---|---|---|---|---|---|---|
Alert 1 | Ketoprofen | 0 | Alert 7 | Efavirenz | 1 | ||
Triamcinolone | 1 | Naproxen | 0 | Ebrotidine | 1 | Nilutamide | 0 |
Prednisone | 1 | Tolmetin | 0 | Niperotidine | 1 | Fluoxetine | 0 |
Prednisolone | 1 | Alert 4 | Penicillamine | 1 | Fluvoxamine | 0 | |
Methylprednisolone | 1 | Zafirlukast | 1 | Nelfinavir | 1 | Sitagliptin | 0 |
Hydrocortisone | 1 | Piroxicam | 1 | Imipenem | 1 | Flucytosine | 0 |
Dexamethasone | 1 | Tipranavir | 1 | Meropenem | 1 | Fluorouracil | 0 |
Cortisone | 1 | Delavirdine | 1 | Disulfiram | 1 | Nilotinib | 0 |
Betamethasone | 1 | Glyburide | 1 | Azathioprine | 1 | Fluphenazine | 0 |
Testosterone | 1 | Glipizide | 1 | Spironolactone | 0 | Celecoxib | 0 |
Stanozolol | 1 | Glimepiride | 1 | Clindamycin | 0 | Clindamycin | 0 |
Oxymetholone | 1 | Gliclazide | 1 | Ceftriaxone | 0 | Riluzole | 0 |
Oxandrolone | 1 | Fosamprenavir | 1 | Ertapenem | 0 | Maraviroc | 0 |
Norethandrolone | 1 | Amprenavir | 1 | Ranitidine | 0 | Chlorambucil | 0 |
Nandrolone | 1 | Tolbutamide | 1 | Nizatidine | 0 | Cyclophosphamide | 0 |
Methyltestosterone | 1 | Tolazamide | 1 | Famotidine | 0 | Lomustine | 0 |
Methenolone | 1 | Chlorpropamide | 1 | Cimetidine | 0 | Melphalan | 0 |
Methandienone | 1 | Acetohexamide | 1 | Thioridazine | 0 | Bendroflumethiazide | 0 |
Fluoxymesterone | 1 | Ebrotidine | 1 | Pergolide | 0 | Methyclothiazide | 0 |
Danazol | 1 | Sudoxicam | 1 | Montelukast | 0 | Polythiazide | 0 |
Exemestane | 0 | Sulfasalazine | 1 | Polythiazide | 0 | Silodosin | 0 |
Spironolactone | 0 | Sulfadiazine | 1 | Albendazole | 0 | Desflurane | 0 |
Dutasteride | −1 | Sulfamethoxazole | 0 | Captopril | 0 | Sevoflurane | 0 |
Finasteride | −1 | Meloxicam | 0 | Cefazolin | −1 | Bicalutamide | 0 |
Eplerenone | −1 | Sildenafil | 0 | Alert 8 | Capecitabine | −1 | |
Alert 2 | Darunavir | 0 | Bromfenac | 1 | Emtricitabine | −1 | |
Diclofenac | 1 | Sulfadoxine | 0 | Tienilic acid | 1 | Mechlorethamine | −1 |
Pirprofen | 1 | Rosuvastatin | 0 | Zomepirac | 1 | Dutasteride | −1 |
Lumiracoxib | 1 | Sotalol | 0 | Clometacin | 1 | Colestipol | −1 |
Fenclozic acid | 1 | Chlorothiazide | 0 | Benziodarone | 1 | Quazepam | −1 |
Fenclofenac | 1 | Polythiazide | 0 | Amiodarone | 1 | Chloral hydrate | −1 |
Clometacin | 1 | Methyclothiazide | 0 | Benzbromarone | 1 | Alert 10 | |
Zomepirac | 1 | Hydrochlorothiazide | 0 | Tolcapone | 1 | Nevirapine | 1 |
Ibufenac | 1 | Bendroflumethiazide | 0 | Fenofibrate | 1 | Trovafloxacin | 1 |
Bromfenac | 1 | Sumatriptan | 0 | Mebendazole | 0 | Abacavir sulfate | 1 |
Benoxaprofen | 1 | Naratriptan | 0 | Indomethacin | 0 | Ciprofloxacin | 1 |
Alclofenac | 1 | Almotriptan | 0 | Ketoprofen | 0 | Saxagliptin | 0 |
Fexofenadine | 0 | Bosentan | 0 | Tolmetin | 0 | Tranylcypromine | 0 |
Ticarcillin | 0 | Probenecid | −1 | Ketorolac | −1 | Gemifloxacin | 0 |
Ibuprofen | 0 | Torsemide | −1 | Alert 9 | Moxifloxacin | 0 | |
Indomethacin | 0 | Vardenafil | −1 | Leflunomide | 1 | Alert 11 | |
Ketoprofen | 0 | Alert 5 | Isoflurane | 1 | Amodiaquine | 1 | |
Naproxen | 0 | Sulfadiazine | 1 | Enflurane | 1 | Ketoconazole | 1 |
Tolmetin | 0 | Bromfenac | 1 | Triamcinolone | 1 | Minocycline | 1 |
Alert 3 | Nomifensine | 1 | Dexamethasone | 1 | Sulfasalazine | 1 | |
Diclofenac | 1 | Amprenavir | 1 | Betamethasone | 1 | Posaconazole | 1 |
Pirprofen | 1 | Fosamprenavir | 1 | Tipranavir | 1 | Acetaminophen | 0 |
Lumiracoxib | 1 | Procainamide | 1 | Pantoprazole | 1 | Itraconazole | 0 |
Fenclozic acid | 1 | Lenalidomide | 1 | Lansoprazole | 1 | Acebutolol | 0 |
Fenclofenac | 1 | Sulfadoxine | 0 | Trifluoperazine | 1 | Lapatinib | 0 |
Clometacin | 1 | Darunavir | 0 | Gemcitabine | 1 | Tigecycline | −1 |
Zomepirac | 1 | Dapsone | 0 | Floxuridine | 1 | Alert 12 | |
Ibufenac | 1 | Sulfamethoxazole | 0 | Mefloquine | 1 | Chlorpromazine | 1 |
Bromfenac | 1 | Alert 6 | Flecainide | 1 | Pipamazine | 1 | |
Benoxaprofen | 1 | Sulindac | 1 | Flutamide | 1 | Perphenazine | 1 |
Alclofenac | 1 | Lansoprazole | 1 | Halothane | 1 | Prochlorperazine | 1 |
Fexofenadine | 0 | Omeprazole | 1 | Fluoxymesterone | 1 | Trifluoperazine | 1 |
Ticarcillin | 0 | Pantoprazole | 1 | Ifosfamide | 1 | Fluphenazine | 0 |
Ibuprofen | 0 | Rabeprazole | 1 | Carmustine | 1 | Thioridazine | 0 |
Indomethacin | 0 | Modafinil | −1 | Tolrestat | 1 | Promethazine | −1 |