Figure 1From: Predicting volume of distribution with decision tree-based regression methods using predicted tissue:plasma partition coefficients Graphical summary of our two-phase approach for predicting log Vss. First, 13 log Kt:p’s (one for each tissue) are the target variables to be predicted from molecular descriptors. Then, the predicted log Kt:p values from these models together with molecular descriptors are used as descriptors to build models predicting log Vss.Back to article page