A multi-label approach to target prediction taking ligand promiscuity into account

Table 2 Distribution of target proteins in different protein families in our ChEMBL17 dataset

	Enzyme	membrane receptor	transcription factor	ion channel	Transporter	cytosolic other	Unclassified	secreted
Number of Classes	209	71	7	4	7	8	1	1
% of Total Classes	67.85 %	23.05 %	2.27 %	1.29 %	2.27 %	2.59 %	0.32 %	0.32 %

90.8 % of the protein targets are enzymes and membrane receptors, with enzymes representing 67.8 % of all the protein targets, and membrane receptors constituting 23 %

ISSN: 1758-2946