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Table 2 Distribution of target proteins in different protein families in our ChEMBL17 dataset

From: A multi-label approach to target prediction taking ligand promiscuity into account

  Enzyme membrane receptor transcription factor ion channel Transporter cytosolic other Unclassified secreted
Number of Classes 209 71 7 4 7 8 1 1
% of Total Classes 67.85 % 23.05 % 2.27 % 1.29 % 2.27 % 2.59 % 0.32 % 0.32 %
  1. 90.8 % of the protein targets are enzymes and membrane receptors, with enzymes representing 67.8 % of all the protein targets, and membrane receptors constituting 23 %