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Table 2 Membrane-receptor data set: comprising 5,031 ligands to classify according to the biological activity they induce on these membrane receptors

From: Verifying the fully “Laplacianised” posterior Naïve Bayesian approach and more

Activity class

Target ID

No. of active compounds

Adenosine A2a receptor

252

424

Adenosine A3 receptor

280

356

Adenosine A1 receptor

114

322

Cannabinoid CB2 receptor

259

319

Histamine H3 receptor

10280

314

Cannabinoid CB1 receptor

87

304

Dopamine D2 receptor

72

281

Mu opioid receptor

129

269

Kappa opioid receptor

137

244

Delta opioid receptor

136

223

Melanocortin receptor 4

10142

220

Serotonin 1a (5-HT1a) receptor

51

215

Dopamine D3 receptor

130

213

Melanin-concentrating hormone receptor 1

19905

206

Serotonin 6 (5-HT6) receptor

10627

173

Serotonin 2a (5-HT2a) receptor

107

155

C-C chemokine receptor type 2

11575

150

Adenosine A2b receptor

278

136

G protein-coupled receptor 44

20174

117

Serotonin 2c (5-HT2c) receptor

108

114

Histamine H4 receptor

11290

96

C-C chemokine receptor type 5

10580

91

Nociceptin receptor

138

89

  1. Columns 1, 2 and 3 denote the protein, the protein identifier (ID) in our dataset and the number of ligands reported for each protein, respectively.