Table 1 Comparison of ChemDIS and CTD
From: ChemDIS: a chemical–disease inference system based on chemical–protein interactions
| ChemDIS | CTD (Apr 5, 2015) | |
|---|---|---|
| Source of interactions for disease inference | STITCH | Manual curation |
| No. of chemical–gene/protein interactions | 4,523,609 (human) |
397,051 (human) 1,041,256 (all species) |
| No. of chemicals (≥1 interacting genes/proteins) | 96,218 (human) |
7,432 (human) 10,837 (all species) |
| No. of chemicals (≥30 interacting genes/proteins) | 14,831 (human) |
1,190 (human) 2,097 (all species) |
| GO analysis | GO | GO |
| Pathway analysis | Reactome and KEGG | Reactome and KEGG |
| Disease analysis | DO and DOLite | MEDIC |
| No. of disease terms |
8,727 (DO) 561 (DOLite) | 11,885 |