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Table 1 A summary of the transporter-related Metrabase content

From: Metrabase: a cheminformatics and bioinformatics database for small molecule transporter data analysis and (Q)SAR modeling

Gene Protein Sub nSub −Mod nInh +Mod nInd
ABCB1 MDR1 566 469 311 113 43 18
ABCG2 BCRP1 310 197 616 24 15 2
SLC15A1 PEPT1 247 95 275 26 7
ABCC2 MRP2 160 139 170 150 102 25
SLC22A1 OCT1 166 95 293 68 3
ABCC1 MRP1 98 91 4 4
SLCO1B1 OATP1B1 97 41 341 50 5 1
SLCO2B1 OATP2B1 48 75 136 203 23
SLCO1B3 OATP1B3 59 36 260 55 10
ABCC3 MRP3 66 24 47 4 17 5
SLCO1A2 OATP1A2 56 24 50 1 1
SLC10A2 ASBT 54 19 11
ABCC4 MRP4 47 19
SLCO3A1 OATP3A1 5 7 6
SLC16A1 MCT1 8 3 30 1
SLCO4A1 OATP4A1 7 1 4
SLC2A1 GLUT1 5 1 21 41
SLCO2A1 OATP2A1 5 1 9 3
SLC51A/B OSTα/β 4 2
SLC7A5 LAT1 2 6
  1. The figures quoted show the number of included compounds for their corresponding actions. Sub, nSub, Mod, nInh, +Mod and nInd refer to substrate, non-substrate, negative modulators (inhibitor and repressor), non-inhibitor, positive modulators (stimulator and inducer) and non-inducer respectively.