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Table 1 A summary of the transporter-related Metrabase content

From: Metrabase: a cheminformatics and bioinformatics database for small molecule transporter data analysis and (Q)SAR modeling

Gene

Protein

Sub

nSub

−Mod

nInh

+Mod

nInd

ABCB1

MDR1

566

469

311

113

43

18

ABCG2

BCRP1

310

197

616

24

15

2

SLC15A1

PEPT1

247

95

275

26

7

–

ABCC2

MRP2

160

139

170

150

102

25

SLC22A1

OCT1

166

95

293

68

3

–

ABCC1

MRP1

98

91

4

4

–

–

SLCO1B1

OATP1B1

97

41

341

50

5

1

SLCO2B1

OATP2B1

48

75

136

203

23

–

SLCO1B3

OATP1B3

59

36

260

55

10

–

ABCC3

MRP3

66

24

47

4

17

5

SLCO1A2

OATP1A2

56

24

50

1

1

–

SLC10A2

ASBT

54

19

11

–

–

–

ABCC4

MRP4

47

19

–

–

–

–

SLCO3A1

OATP3A1

5

7

6

–

–

–

SLC16A1

MCT1

8

3

30

1

–

–

SLCO4A1

OATP4A1

7

1

4

–

–

–

SLC2A1

GLUT1

5

1

21

41

–

–

SLCO2A1

OATP2A1

5

1

9

3

–

–

SLC51A/B

OSTα/β

4

2

–

–

–

–

SLC7A5

LAT1

2

–

6

–

–

–

  1. The figures quoted show the number of included compounds for their corresponding actions. Sub, nSub, −Mod, nInh, +Mod and nInd refer to substrate, non-substrate, negative modulators (inhibitor and repressor), non-inhibitor, positive modulators (stimulator and inducer) and non-inducer respectively.