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Fig. 6 | Journal of Cheminformatics

Fig. 6

From: Synergy Maps: exploring compound combinations using network-based visualization

Fig. 6

Synergy Map, represented under t-SNE reduced biological space. Biological space, with various clusters annotated according to hypothesized mode of action or drug function. It appears that the HDAC inhibitor cluster (Including Quisinostat, Trichostatin A and Panobinostat) tends to be disproportionately synergistic compared to other clusters, whilst the PI3K/mTOR inhibitors exhibit disproportional antagonism.

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