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Table 5 Descriptions used for the ChEMBL confidence scores

From: Target prediction utilising negative bioactivity data covering large chemical space

Confidence score

Description

0

Default value—target assignment has yet to be curated

1

Target assigned is non-molecular

3

Target assigned is molecular non-protein target

4

Multiple homologous protein targets may be assigned

5

Multiple direct protein targets may be assigned

6

Homologous protein complex subunits assigned

7

Direct protein complex subunits assigned

8

Homologous single protein target assigned

9

Direct single protein target assigned

  1. A confidence score of 5 was used in this study to ensure that multi-domain proteins are not excluded from training data. Confidence scores of 9 or 8 are frequently used which specify homologous or direct proteins to be assigneds