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Fig. 1 | Journal of Cheminformatics

Fig. 1

From: Predictiveness curves in virtual screening

Fig. 1

Schematic diagram presenting how performance metrics relate to the predictiveness curve. Displaying the PC allows for an intuitive selection of thresholds. Performance metrics related to a chosen threshold are easily interpreted from the curve. a Partial total gain (pTG): hatched area/blue frame; total gain (TG): blue area. b True positive fraction (TPF): blue area/area under activity prevalence; false positive fraction (FPF): red area/(1-area under activity prevalence); positive predictive value (PPV): blue area/blue frame; negative predictive value (NPV): white area/red frame

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