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Table 8 Library ranking based on similarity to Kalydeco

From: A reliable computational workflow for the selection of optimal screening libraries

Library Substructure-based Pharmacophore-based Fingerprint-based Total ranka
Elite libraries 7 6 4 17 (6)
Platinum collection 2 7 1 10 (2)
DIVERSet™-CL 7 1 5 13 (4)
DIVERSet™-EXP 1 2 2 5 (1)
Drug-like set 3 3 6 12 (3)
Pharmacological diversity set 4 4 7 15 (5)
Maybridge screening collection 5 5 2 12 (3)
Prestwick Chemical Library® 7 8 8 23 (7)
MSII full library 6 8 3 17 (6)
  1. aThe “Total rank” column provides the sum of all rankings and in parenthesis, the final rank of each library