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Table 3 Predictive results of SEA models with different pharmacophore representations of compounds in fingerprints

From: Improving chemical similarity ensemble approach in target prediction

Points of pharmacophore Bin shape Accuracy Precision Sensitivity Specificity \(F_{0.5}{\text{-}}Measure\) \(F_{0.25}{\text{-}}Measure\)
2 (0,2), (2,5), (5,8) 0.513 0.479 0.567 0.466 0.494 0.483
2, 3 (0,2), (2,5), (5,8) 0.642 0.678 0.436 0.821 0.61 0.657
2, 3 (2, 3), (3, 4), (4, 5), (5, 6), (6, 7), (7, 20) 0.667 0.752 0.42 0.88 0.65 0.719