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Table 3 Predictive results of SEA models with different pharmacophore representations of compounds in fingerprints

From: Improving chemical similarity ensemble approach in target prediction

Points of pharmacophore

Bin shape

Accuracy

Precision

Sensitivity

Specificity

\(F_{0.5}{\text{-}}Measure\)

\(F_{0.25}{\text{-}}Measure\)

2

(0,2), (2,5), (5,8)

0.513

0.479

0.567

0.466

0.494

0.483

2, 3

(0,2), (2,5), (5,8)

0.642

0.678

0.436

0.821

0.61

0.657

2, 3

(2, 3), (3, 4), (4, 5), (5, 6), (6, 7), (7, 20)

0.667

0.752

0.42

0.88

0.65

0.719