Table 3 Summary of MMPs and cliffs for the combined AR dataset
From: Cheminformatics analysis of the AR agonist and antagonist datasets in PubChem
MOA pattern | Number of MMPs | Left molecule | Right molecule | |||
|---|---|---|---|---|---|---|
Agonist | Antagonist | Agonist | Antagonist | |||
Same MOA | 64 | 17 | Active | Active | Active | Active |
26 | Inactive | Active | Inactive | Inactive | ||
21 | Active | Inactive | Active | Inactive | ||
Weak MOA-cliffs | 13 | 7 | Inactive | Active | Active | Active |
6 | Active | Active | Active | Inactive | ||
Strong MOA-cliffs | 1 | 1 | Active | Inactive | Inactive | Active |