Fig. 5
From: An activity canyon characterization of the pharmacological topography
i Network of 91 distinctive interactions determined by s below average. ii Network of 39 distinctive interactions determined by d above average. iii Network of 11 distinctive interactions determined by d by calculation for \(d \ge \mu_{d} + \sigma_{d} .\) The medicine pairs are (Lysine–Ornithone), (Adenosine monophosphate–Adenosine triphosphate), (Vitamin A–Alitretinoin), (Vitamin A–Tretinoin), (Vitamin A–Isotretinoin), (Propoiomazine–Aceprometazine), (Loxapine–Amoxapine), (Dicloxacillin–Cloxacillin), (Pseudoephidrine–Ephedrine), (Tioconazole–Miconazole), (Felodipine–Clevidipine)