Post-acquisition filtering of salt cluster artefacts for LC-MS based human metabolomic studies

Table 1 Percent data reduction after mass defect filtering alone or in combination with retention time and hmdb inclusion list

Ionization mode	Filter	Features remaining	% Features removed
Positive	None	2227	0.00
	md	1730	22.32
	md + RT	1853	16.79
	md + RT + inclusion	1872	15.94
Negative	None	1742	0.00
	md	1107	36.45
	md + RT	1225	29.68
	md + RT + inclusion	1246	28.47

All features detected in plasma in the malnutrition dataset are shown in both positive and negative ionization mode
RT retention time, md mass defect

ISSN: 1758-2946