Fig. 6
From: Mapping the 3D structures of small molecule binding sites
Heat map of SiteHopper PatchScores across the Pilot dataset of 1085 protein structures represented by 1706 conserved potential binding sites. Binding sites are grouped within individual protein targets on the x-axis and a global hierarchical clustering is shown on the y-axis. A similarity score of 0 and 4 indicates complete dissimilarity and perfect similarity, respectively. Similarity between potential binding sites derived from different protein targets, cationic trypsin and prothrombin, is highlighted in red