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Table 2 Summary of performance of QSAR models for predicting the oligomeric state of FPs (100% homologous sequence reduction) using the J48 algorithm

From: osFP: a web server for predicting the oligomeric states of fluorescent proteins

Descriptors

Training set

Tenfold CV set

External set

Ac (%)

Sn (%)

Sp (%)

MCC

Ac (%)

Sn (%)

Sp (%)

MCC

Ac (%)

Sn (%)

Sp (%)

MCC

AAC/DPC/TPC

97.40 ± 0.77

97.72 ± 1.23

97.14 ± 1.31

0.95 ± 0.02

83.07 ± 2.04

83.26 ± 2.19

82.95 ± 2.27

0.66 ± 0.04

83.26 ± 3.58

83.77 ± 5.14

83.37 ± 4.45

0.67 ± 0.07

AC

98.70 ± 0.58

98.54 ± 0.93

98.86 ± 0.75

0.97 ± 0.01

78.36 ± 2.35

78.36 ± 2.36

78.67 ± 2.30

0.57 ± 0.04

78.49 ± 4.76

78.65 ± 5.66

78.89 ± 5.62

0.57 ± 0.10

CTD

97.58 ± 0.82

98.05 ± 0.99

97.20 ± 1.33

0.95 ± 0.02

80.28 ± 2.37

79.66 ± 2.98

80.88 ± 2.33

0.60 ± 0.05

80.40 ± 4.92

80.37 ± 6.63

81.01 ± 5.34

0.61 ± 0.10

Ctriad

95.46 ± 1.08

96.20 ± 1.51

94.85 ± 1.87

0.91 ± 0.02

80.38 ± 2.01

81.07 ± 2.43

79.82 ± 2.08

0.61 ± 0.04

81.06 ± 4.83

81.80 ± 5.79

80.98 ± 5.55

0.62 ± 0.10

QSO

98.35 ± 0.63

98.35 ± 0.83

98.36 ± 0.93

0.97 ± 0.01

80.15 ± 1.91

80.11 ± 2.25

80.27 ± 2.16

0.60 ± 0.04

81.42 ± 4.00

81.86 ± 5.21

81.58 ± 5.00

0.63 ± 0.08

PseAAC

98.51 ± 0.62

98.63 ± 0.85

98.42 ± 1.05

0.97 ± 0.01

81.13 ± 1.89

81.19 ± 2.24

81.14 ± 2.09

0.62 ± 0.04

81.40 ± 4.66

81.13 ± 5.48

82.19 ± 5.54

0.63 ± 0.09