ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics

Table 2 Performances of fivefold cross-validation for 18 targets using SVM

Target	Active compounds	Inactive compounds	Ratio (active/inactive compounds)	Sensitivity	Precision	Specificity	κ
PPARA	1955	1465	1.33	0.96	0.94	0.92	0.89
MMP2	2742	2363	1.16	0.96	0.96	0.96	0.92
MAOA	732	733	1.00	0.79	0.80	0.81	0.59
NR1I2	249	1090	0.23	0.82	0.73	0.93	0.72
TMPRSS15	139	724	0.19	0.43	0.54	0.93	0.39
HSD17B10	3410	11,510	0.30	0.41	0.40	0.82	0.23
KDM4E	3938	35,059	0.11	0.22	0.29	0.94	0.18
LMNA	14,533	171,164	0.09	0.49	0.13	0.72	0.10
TDP1	23,133	276,782	0.08	0.76	0.38	0.90	0.45
TARDBP	12,193	387,934	0.03	0.22	0.08	0.92	0.08
ALOX15	1932	69,362	0.03	0.49	0.12	0.90	0.16
BRCA1	8619	363,912	0.02	0.72	0.20	0.93	0.29
DRD2	4613	343,076	0.01	0.96	0.93	1.00	0.94
GSK3B	3334	300,186	0.01	0.85	0.72	1.00	0.78
JAK2	2158	213,915	0.01	0.85	0.81	1.00	0.83
POLK	773	389,418	0.002	0.55	0.17	0.99	0.26
FEN1	1050	381,575	0.003	0.35	0.03	0.96	0.04
HDAC3	369	311,425	0.001	0.98	0.76	1.00	0.86

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