Fig. 2

Evaluation of the ability of the programs in detecting the correct poses. For each target, the rank of the best pose is reported with respect to its RMSD from the crystal structure. The rank can range between 1 and 30, since there are at most 30 poses/target. For Glide, Surflex and Gold the RMSDs are less than 10 Å, whereas for FlexX they can reach 18 Å