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Fig. 4 | Journal of Cheminformatics

Fig. 4

From: Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR

Fig. 4

PCA transformation of the Ambit 2011 dataset, highlighting Alk, Met, and EGFR kinases. Of the first three dimensions of the principal component transformation of the dataset, prinicpal component #3 clearly distinguishes EGFR and variants from the other kinases, while ALK, MET, and EGFR all are similar with respect to PC #1. PC #2 distinguishes the T790M mutants from the other EGFR forms

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