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Table 3 Performance of QSAR based predictive models developed on each of the HIV protein inhibitor (IC50) datasets during tenfold training/testing and on independent validation

From: HIVprotI: an integrated web based platform for prediction and design of HIV proteins inhibitors

Serial number HIV protein Inhibitor compounds Number of selected descriptors Pearson’s correlation coefficient (PCC) p value
Total Training/testing Independent validation Training/testing (10×) Independent validation
1 Protease 1895 1706 189 45 0.78 0.73 1.00e−9
2 Reverse transcriptase 2126 1914 212 61 0.76 0.72 1.00e−7
3 Integrase 1240 1116 124 55 0.74 0.70 1.00e−6