From: HIVprotI: an integrated web based platform for prediction and design of HIV proteins inhibitors
Serial number | Target | Predictive method and compounds type | Number of compounds | Correlation | Web server/software | Year | References |
---|---|---|---|---|---|---|---|
1 | Protease | Non-peptide inhibitors | 46 | 0.93–0.98 | No | 2010 | [57] |
2 | Cycloalkylpyranone based compounds | 170 | 0.6–0.83 | No | 2010 | [58] | |
3 | Ritonavir analogs | 177 | 0.85 | No | 2012 | [59] | |
4 | Protease inhibitors | 37 | 0.85–0.86 | No | 2015 | [55] | |
5 | Hydroxyethylamine derivatives | 180 | 0.86 | No | 2015 | [60] | |
6 | Chemically diverse | 1895 | 0.78 | Yes | 2017 | HIVprotI | |
7 | Reverse transcriptase | Amino-arylsulfonylbenzonitriles | 68 | 0.86 | No | 2009 | [61] |
8 | TIBO derivatives | 70 | 0.83–0.88 | No | 2009 | [62] | |
9 | PETT derivatives | 61 | 0.77–0.83 | No | 2009 | [63] | |
10 | HEPT derivatives | 36 | 0.92 | No | 2011 | [64] | |
11 | Substituted benzoxazinones | 33 | 0.8 | No | 2012 | [65] | |
12 | Non-nucleoside inhibitors | 80 | 0.7–0.8 | No | 2014 | [66] | |
13 | Chemically diverse | 2126 | 0.76 | Yes | 2017 | HIVprotI | |
14 | Integrase | Carboxylic acid derivatives | 62 | 0.72–0.87 | No | 2010 | [67] |
15 | N-methyl pyrimidones | 51 | 0.84 | No | 2011 | [43] | |
16 | Quinoline ring derivatives | 77 | 0.98 | No | 2012 | [42] | |
17 | Curcumine derivatives | 39 | 0.91 | No | 2013 | [68] | |
18 | Chemically diverse | 1240 | 0.74 | Yes | 2017 | HIVprotI |