Fig. 3
From: RepTB: a gene ontology based drug repurposing approach for tuberculosis
Predicted drugs for top 10 Mtb targets. The predicted targets are colored in pink. The known drug nodes of the targets are colored in green. The green edges show the known DTIs from the network. The dotted red line shows the highly similar (dissimilarity coefficient of 0.15) known and predicted drug for the specific target. Known and predicted drugs for FolP1, MenB, FtsZ and Tmk were observed to be structurally similar (panels a–d), no significant structural similarity was observed between the known and predicted drugs for Dut, InhA, RibH and MshD (panels e–h)