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Table 1 Performance evaluation comparison between TLHNSMMA and SMiR-NBI in global LOOCV, SM-fixed local LOOCV, miRNA-fixed local LOOCV and fivefold cross validation based on Dataset 1 and Dataset 2

From: Inferring potential small molecule–miRNA association based on triple layer heterogeneous network

Dataset Experimental types TLHNSMMA SMiR-NBI
Dataset 1 AUC in global LOOCV 0.9859 0.8843
AUC in SM-fixed local LOOCV 0.7645 0.7497
AUC in miRNA-fixed local LOOCV 0.9845 0.8837
Average AUC in fivefold cross validation 0.9851 ± 0.0012 0.8554 ± 0.0063
Dataset 2 AUC in global LOOCV 0.8149 0.7264
AUC in SM-fixed local LOOCV 0.6057 0.6100
AUC in miRNA-fixed local LOOCV 0.8244 0.7846
Average AUC in fivefold cross validation 0.8168 ± 0.0022 0.7104 ± 0.0087
  1. The corresponding AUCs of TLHNSMMA are shown in the third columns, and compared with the AUCs for SMiR–NBI in the fourth column