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Table 1 Performance evaluation comparison between TLHNSMMA and SMiR-NBI in global LOOCV, SM-fixed local LOOCV, miRNA-fixed local LOOCV and fivefold cross validation based on Dataset 1 and Dataset 2

From: Inferring potential small molecule–miRNA association based on triple layer heterogeneous network

Dataset

Experimental types

TLHNSMMA

SMiR-NBI

Dataset 1

AUC in global LOOCV

0.9859

0.8843

AUC in SM-fixed local LOOCV

0.7645

0.7497

AUC in miRNA-fixed local LOOCV

0.9845

0.8837

Average AUC in fivefold cross validation

0.9851 ± 0.0012

0.8554 ± 0.0063

Dataset 2

AUC in global LOOCV

0.8149

0.7264

AUC in SM-fixed local LOOCV

0.6057

0.6100

AUC in miRNA-fixed local LOOCV

0.8244

0.7846

Average AUC in fivefold cross validation

0.8168 ± 0.0022

0.7104 ± 0.0087

  1. The corresponding AUCs of TLHNSMMA are shown in the third columns, and compared with the AUCs for SMiR–NBI in the fourth column