Table 3 Event types
From: Annotation and detection of drug effects in text for pharmacovigilance
Event type | Definition | Possible participants |
|---|---|---|
Adverse_effect (AE) | A pharmacological substance or combination/interaction between pharmacological substances has an effect on the body that is considered to be undesirable. More specifically, the substance, combination or interaction causes a disorder to manifest itself, or to become worse | has_agent: Pharmacological substance or combination/interaction of substances responsible for the adverse effect affects: Disorder resulting from or worsened by administration of the Agent has_subject: The individual or group in which the drug effect is specified to occur |
Potential_therapeutic_effect (PTE) | A pharmacological substance or combination/interaction of pharmacological substances is being administered, with the intention of having a therapeutic effect | has_agent: Pharmacological substance or combination/interaction of substances responsible for the therapeutic effect affects: Disorder improved or cured by administration of the Agent has_subject: Individual or group in which the therapeutic effect is specified to occur |
Combination | A specification that two or more pharmacological substances are being used at the same time (e.g., they have been co-administered) | has_participant: A pharmacological substance being combined/co-administered |
DDI | A specific mention that there is an interaction between two or more pharmacological substances | has_participant: A pharmacological substance involved in the interaction has_subject: Individual or group in which the DDI is specified to occur |