Table 6 Targets selected by the target pharmacophore screening with fit value > 0.9
ID | Uniprot ID | Gene name | Title | Family |
|---|---|---|---|---|
3ac3 | P06239 | LCK_HUMAN | Tyrosine-protein kinase Lck | Protein kinase |
3ad4 | P06239 | LCK_HUMAN | Tyrosine-protein kinase Lck | Protein kinase |
3mzs | P00189 | CP11A_BOVIN | Cholesterol side-chain cleavage enzyme, mitochondrial | Cytochrome P450 |
3my0 | P37023 | ACVL1_HUMAN | Serine/threonine-protein kinase receptor R3 | Protein kinase |
1lox | P12530 | LOX15_RABIT | Arachidonate 15-lipoxygenase | Lipoxygenase |
1qyx | P14061 | DHB1_HUMAN | Estradiol 17-beta-dehydrogenase 1 | Short chain dehydrogenases/reductases (SDR) |
2bik | P11309 | PIM1_HUMAN | Serine/threonine-protein kinase pim-1 | Protein kinase |
2br1 | O14757 | CHK1_HUMAN | Serine/threonine-protein kinase Chk1 | Protein kinase |
2chw | P48736 | PK3CG_HUMAN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PI3/PI4 kinase |
2chz | P48736 | PK3CG_HUMAN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PI3/PI4 kinase |
2p0m | P12530 | LOX15_RABIT | Arachidonate 15-lipoxygenase | Lipoxygenase |
2wxq | Q3UDT3 | Q3UDT3_MOUSE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | PI3/PI4 kinase |
3ddu | P48147 | PPCE_HUMAN | Prolyl endopeptidase | Peptidase S9A |
3h3c | Q14289 | FAK2_HUMAN | Protein-tyrosine kinase 2-beta | Protein kinase |
3hrb | Q16539 | MK14_HUMAN | Mitogen-activated protein kinase 14 | Protein kinase |
3le6 | P24941 | CDK2_HUMAN | Cyclin-dependent kinase 2 | Protein kinase |
3mqe | Q05769 | PGH2_MOUSE | Prostaglandin G/H synthase 2 | Prostaglandin G/H synthase |
3p2v | P15121 | ALDR_HUMAN | Aldose reductase | Aldo/keto reductase |
3r7r | P48736 | PK3CG_HUMAN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PI3/PI4 kinase |
3rgz | O22476 | BRI1_ARATH | Protein brassinosteroid insensitive 1 | Protein kinase |
3s3g | P15121 | ALDR_HUMAN | Aldose reductase | Aldo/keto reductase |
3tfq | P28845 | DHI1_HUMAN | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Short chain dehydrogenases/reductases (SDR) |
3ugr | P42330 | AK1C3_HUMAN | Aldo-keto reductase family 1 member C3 | Aldo/keto reductase |
3zrl | P49841 | GSK3B_HUMAN | Glycogen synthase kinase-3 beta | Protein kinase |
4a79 | P27338 | AOFB_HUMAN | Amine oxidase [flavin-containing] B | Flavin monoamine oxidase |
2hpy | P02699 | OPSD_BOVIN | Rhodopsin | G-protein coupled receptor 1 |
3gql | P11362 | FGFR1_HUMAN | Fibroblast growth factor receptor 1 | Protein kinase |
2ab2 | P08235 | MCR_HUMAN | Mineralocorticoid receptor | Nuclear hormone receptor |
3lmp | P37231 | PPARG_HUMAN | Peroxisome proliferator-activated receptor gamma | Nuclear hormone receptor |
1pzo | P62593 | BLAT_ECOLX | Beta-lactamase TEM | Class-A beta-lactamase |
1zhx | P35844 | KES1_YEAST | Oxysterol-binding protein homolog 4 | Oxysterol-binding protein |
1zhz | P35844 | KES1_YEAST | Oxysterol-binding protein homolog 4 | Oxysterol-binding protein |
2oxd | P28523 | CSK2A_MAIZE | Casein kinase II subunit alpha | Protein kinase |
2x00 | Q8WSF8 | Q8WSF8_APLCA | Soluble acetylcholine receptor | Neurotransmitter-gated ion-channel |
3hgy | Q7B8P6 | Q7B8P6_CAMJU | cmeR | Transcriptional regulator |
3ov4 | P00947 | SDIS_COMTE | Steroid delta-isomerase | Steroid delta-5-4-isomerase |
3s92 | Q15059 | BRD3_HUMAN | Bromodomain-containing protein 3 | Bromodomain and extraterminal domain |
3smo | P31947 | 1433S_HUMAN | 14-3-3 protein sigma | 14-3-3 protein |
4a01 | O22124 | O22124_VIGRA | Pyrophosphate-energized vacuolar membrane proton pump | H(+)-translocating pyrophosphatase (TC 3.A.10) |
4a86 | P15494 | BEV1A_BETPN | Major pollen allergen Bet v 1-A | Bet v I type allergen |
4a8v | P43183 | BEV1J_BETPN | Major pollen allergen Bet v 1-J | Bet v I type allergen |
2iws | P02829 | HSP82_YEAST | ATP-dependent molecular chaperone HSP82 | Heat shock protein Hsp90 |
3b27 | P07900 | HS90A_HUMAN | Heat shock protein HSP 90-alpha | Heat shock protein Hsp90 |
2xa4 | O60674 | JAK2_HUMAN | Tyrosine-protein kinase JAK2 | Protein kinase |
4a9n | P25440 | BRD2_HUMAN | Bromodomain-containing protein 2 | Bromodomain and extraterminal domain |
4alh | P25440 | BRD2_HUMAN | Bromodomain-containing protein 2 | Bromodomain and extraterminal domain |
3svg | O60885 | BRD4_HUMAN | Bromodomain-containing protein 4 | Bromodomain and extraterminal domain |