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Table 7 Leishmania donovani homologous targets from PSIBLAST search wit evalue < 3

From: Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors

Uniprot ID Gene name Title %Identity Evalue Bit score Query
P27890 HSP83_LEIDO Heat shock protein 83 61.76 0 568 P07900|HS90A_HUMAN
Q01440 GTR1_LEIDO Membrane transporter D1 34.83 0.004 30.8 P21616|AVP_VIGRR
A4ZZ93 DHYSL_LEIDO Inactive deoxyhypusine synthase 19.70 0.042 26.2 P42330|AK1C3_HUMAN
P39050 TYTR_LEIDO Trypanothione reductase 64.71 0.051 27.7 P11362|FGFR1_HUMAN
E9BDA8 GMPR_LEIDB GMP reductase 25.64 0.073 25.4 P24941|CDK2_HUMAN
P43151 GPA_LEIDO Putative guanine nucleotide-binding protein subunit alpha 27.03 0.099 25.4 P49841|GSK3B_HUMAN
P17804 HSP70_LEIDO Heat shock 70 kDa protein 33.33 0.24 23.9 P62593|BLAT_ECOLX
P36889 SAHH_LEIDO Adenosylhomocysteinase 26.72 0.24 23.5 P28845|DHI1_HUMAN
A7LBL2 PURA_LEIDO Adenylosuccinate synthetase 27.66 0.27 25 Q15059|BRD3_HUMAN
Q27675 CYAA_LEIDO Receptor-type adenylate cyclase A 29.73 0.31 21.6 P00947|SDIS_COMTE
P23223 GP63_LEIDO Leishmanolysin 37.84 0.33 24.3 P37231|PPARG_HUMAN
Q25263 CYAB_LEIDO Receptor-type adenylate cyclase B 28.36 0.52 24.6 Q3UDT3|Q3UDT3_MOUSE
P21620 IMDH_LEIDO Inosine-5’-monophosphate dehydrogenase 47.37 0.57 22.7 P15121|ALDR_HUMAN
Q9BIC6 PFKA_LEIDO ATP-dependent 6-phosphofructokinase 28.95 0.59 22.7 P14061|DHB1_HUMAN
Q05889 LPG1_LEIDO Galactofuranosyl glycosyltransferase 28.07 0.69 24.6 O60885|BRD4_HUMAN
D9IFD5 DOHH_LEIDO Deoxyhypusine hydroxylase 38.46 0.71 23.1 P37023|ACVL1_HUMAN
Q01441 GTR2_LEIDO Membrane transporter D2 38.46 0.79 23.1 P27338|AOFB_HUMAN
P12522 ATXB_LEIDO Probable proton ATPase 1B 25.69 1.1 22.3 P35844|KES1_YEAST
P11718 ATXA_LEIDO Probable proton ATPase 1A 25.23 1.2 22.3 P35844|KES1_YEAST
O00874 DPOLA_LEIDO DNA polymerase alpha catalytic subunit 22.22 1.2 23.1 P48147|PPCE_HUMAN
P55905 COQ5_LEIDO 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 41.18 1.5 22.3 P02829|HSP82_YEAST
Q05885 ARD1_LEIDO N-terminal acetyltransferase complex ARD1 subunit homolog 32.56 1.6 21.9 P02829|HSP82_YEAST
P12522 ATXB_LEIDO Probable proton ATPase 1B 50 1.8 21.6 P35844|KES1_YEAST
P27116 DCOR_LEIDO Ornithine decarboxylase 29.55 2.2 22.7 P48736|PK3CG_HUMAN
Q36736 KM11_LEIDO Kinetoplastid membrane protein 11 27.59 2.6 19.2 P31947|1433S_HUMAN
Q25264 DCAM_LEIDO S-adenosylmethionine decarboxylase proenzyme 42.11 2.7 21.6 Q15059|BRD3_HUMAN
B5APK2 DHYS_LEIDO Deoxyhypusine synthase 36.36 2.9 20.4 P28845|DHI1_HUMAN