Fig. 9
From: Implicit-descriptor ligand-based virtual screening by means of collaborative filtering
Correlation of AUC and AVE bias. Illustration of the performance of Implicit method using collaborative filtering,Random Forest and KNN algorithms using explicit features for targets with greater than 100 assays in training set. Both Random Forest and KNN show clear correlation between AVE bias and AUC while the collaborative filtering is impervious to the presence of AVE Bias.The Pearson correlation for the Random Forest method was found to be 0.69, the K-Nearest Neighbor method was 0.74, and the collaborative filtering algorithm using implicit fingerprints was 0.07