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TableĀ 2 Synthetic route identification for 919 known drug structures using RTSA-Design and a range of RRT-Repositories

From: A retrosynthetic analysis algorithm implementation

RRT set RTSA results (structures with at least one route) Coverage Average number of routes
RRT-0-10 917 917/919 922,449/917
RRT-0-100 917 917/919 101,309/917
RRT-0-1000 917 917/919 21,255/917
RRT-0-10000 831 831/919 3319/831
RRT-1-10 916 916/919 24,209/916
RRT-1-100 905 905/919 9497/905
RRT-1-1000 835 835/919 4076/835
RRT-1-10000 327 327/919 423/327
RRT-2-10 841 841/919 6620/841
RRT-2-100 756 756/919 2344/756
RRT-2-1000 284 284/919 455/284
RRT-2-10000 52 52/919 53/52