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Table 1 Statistics for each of the five transformer modules: (1) EC-based module (Enzyme Commission-based metabolism); (2) CYP450 module (Cytochrome P450 metabolism); (3) human gut microbial module (Human gut microbial metabolism); (4) Phase II module (Phase II metabolism), and (5) environmental microbial module (Environmental microbial degradation)

From: BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification

 

Number of enzymes

Number of biotransformation rules

Number of enzyme-rule associations

Number of covered biosystems

EC-based (ecbased)

285

408

459

2

CYP450 (cyp450)

9

163

712

1

Human gut microbial (hgut)

53

201

204

2

Phase II (phaseII)

9

74

81

2

Environmental microbial (envmicro)

1

301

301

1

  1. The codes/abbreviations in the first column are the names of options used programmatically to specify the module of interest