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Table 2 Dependence on C° of mean changes in ligand efficiency for F2L programs surveyed in [76]

From: The nature of ligand efficiency

C°/Ma

Mean Δη bbind

SE Δη cbind

Prob > |t|d

0.001

+ 0.087

0.012

< 0.001

0.01

+ 0.055

0.015

0.001

0.1

+ 0.024

0.018

0.20

1.0

− 0.008

0.021

0.69

10

− 0.04

0.024

0.11

  1. aStandard concentration
  2. bMean change in ligand efficiency as defined in (11)
  3. cStandard error in mean change in ligand efficiency as defined in (11)
  4. dP value for matched pair t test