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Table 2 RF and SOHN trained with ChEMBL data against the Merck test data

From: Avoiding hERG-liability in drug design via synergetic combinations of different (Q)SAR methodologies and data sources: a case study in an industrial setting

Statistical models (public) ACC BA SENS SPEC PPV NPV MCC KAPPA
RFChEMBL 0.74 0.57 0.26 0.88 0.37 0.81 0.16 0.15
SOHNChEMBL 0.73 0.66 0.54 0.78 0.42 0.86 0.30 0.29