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Table 8 Combining statistical models

From: Avoiding hERG-liability in drug design via synergetic combinations of different (Q)SAR methodologies and data sources: a case study in an industrial setting

Models ACC BA SENS SPEC PPV NPV MCC KAPPA
RFMerck+ChEMBL (2:5) 0.84 0.75 0.59 0.91 0.65 0.89 0.52 0.51
SOHNMerck+ChEMBL (2:5) 0.83 0.76 0.63 0.89 0.62 0.89 0.52 0.52
RF-SOHNMerck+ChEMBL (2:5) 0.85 0.78 0.66 0.91 0.67 0.90 0.57 0.57