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Fig. 1 | Journal of Cheminformatics

Fig. 1

From: Detecting drug communities and predicting comprehensive drug–drug interactions via balance regularized semi-nonnegative matrix factorization

Fig. 1

The illustration of a comprehensive DDI network. (1) The left panel shows the DDI network. Four communities are highlighted by dashed curves. Most edges within communities are positive or negative while most edges between communities are negative. Blue single lines and yellow double lines denote enhancive and degressive interactions respectively. (2) The right panel lists four types of triads, including two strongly balanced triads (PPP and NNP), one weakly balanced triad (NNN) and one unbalanced triad (PPN). The numbers in the triads show the number of occurrences of this structure in the network (e.g. PPP appears 4 times in the network)

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Journal of Cheminformatics

ISSN: 1758-2946

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